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To calculate Cost of Goods Sold (COGS), first determine the gross profit by multiplying net sales by the gross profit margin. For example, with $100,000 net sales and a 40% gross profit margin, gross profit is $40,000. COGS is then calculated by subtracting gross profit from net sales, resulting in $60,000. COGS represents the direct costs associated with producing the goods sold during the accounting period.

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